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Over the Andes to Mendoza

Santiago | Chile

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A road trip itinerary across the Andes from Santiago and Valparaíso to Mendoza wine country.

This 7-day journey from Santiago to Mendoza is shaped by contrast and elevation. It begins with design and architecture in Chile’s capital, followed by coastal color along the Pacific, before turning toward the Andes for one of South America’s most iconic mountain crossings. Guided experiences anchor key moments, from urban exploration to vineyard tastings and gaucho traditions, while the road itself carries you across borders and into dramatically changing landscapes. It is ideal for travelers who enjoy movement, culture, and the shift from the Pacific coast to high mountain desert.
DAY 1 – SANTIAGO BY DESIGN | Your journey begins with a full-day guided architectural tour through Santiago’s historic civic center. Plazas, neighborhoods, and contemporary landmarks reveal how the city has evolved through politics, innovation, and design. After the tour, the evening is yours to explore on foot from your central base. Staying in a walkable district allows you to settle in and experience Santiago at street level.
DAY 2 – VALPARAÍSO AND VIÑA DEL MAR | Today is a guided day trip to the coast, combining fine art, street murals, and wine tasting. You move between the hills of Valparaíso and the elegance of Viña del Mar, experiencing both urban creativity and seaside atmosphere. The long day is balanced by returning to the same hotel in Santiago, keeping logistics simple before the road portion begins.
DAY 3 – SANTIAGO TO LOS ANDES | In the morning, you pick up your rental car and drive northeast toward Los Andes, gradually entering vineyard landscapes and Andean foothills. The short drive introduces the shift from city to mountain terrain. In the evening, a guided stargazing experience explores how Indigenous cultures interpreted the night sky, adding a new dimension to the landscape around you.
DAY 4 – ACROSS THE ANDES TO MENDOZA | Today is dedicated to the crossing itself. You follow the Caracoles Road, a series of dramatic switchbacks climbing toward the Chile-Argentina border. Stops at Laguna del Inca and viewpoints along the way reveal the scale of the Andes, and Aconcagua appears as you descend into Argentina. After border formalities, you arrive in Mendoza by early evening and settle into your new base.
DAY 5 – MENDOZA WINE AND CRAFT | The morning begins with a guided wine and olive oil experience in the Mendoza countryside, combining tastings with a relaxed seasonal lunch. In the evening, you join a ceramic workshop with a local artisan, blending storytelling, hands-on creation, and regional wine. The day moves between rural estates and creative city life.
DAY 6 – ANDES FOOTHILLS AND GAUCHO TRADITION | You drive west toward Cacheuta, following the Mendoza River into the Andes foothills. The scenery becomes rugged and expansive before you return to Mendoza. In the late afternoon, a guided horseback ride into the Andes introduces gaucho culture, ending with a sunset gathering and traditional meal by the fire.
DAY 7 – MENDOZA TO BUENOS AIRES | After breakfast, you transfer to Mendoza Airport for your flight to Buenos Aires. The short journey across the Andes brings you from vineyard country to Argentina’s capital, where the next chapter of your travels begins.
PLAN YOUR TRIP WITH FERNWAYER | Book directly from the itinerary and choose your own hotels and restaurants. Download the iOS app to make the journey your own.
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Self-Explore X Fernwayer, September 2025
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JOURNEY


DAY 1:

Guided architectural tour through Santiago’s civic center and design landmarks.

DAY 2:

Coastal art, street murals, and wine tasting in Valparaíso and Viña del Mar.

DAY 3:

Drive to Los Andes and guided stargazing in the Andean foothills.

DAY 4:

Scenic Andes crossing via Caracoles Road to arrive in Mendoza.

DAY 5:

Wine and olive oil tastings by day, ceramic workshop with local artisan by night.

DAY 6:

Drive to Cacheuta and sunset horseback ride with gaucho culture in the Andes.

DAY 7:

Flight from Mendoza across the Andes to Buenos Aires.

View Journey Details

JOURNEY


DAY 1:

Guided architectural tour through Santiago’s civic center and design landmarks.

DAY 2:

Coastal art, street murals, and wine tasting in Valparaíso and Viña del Mar.

DAY 3:

Drive to Los Andes and guided stargazing in the Andean foothills.

DAY 4:

Scenic Andes crossing via Caracoles Road to arrive in Mendoza.

DAY 5:

Wine and olive oil tastings by day, ceramic workshop with local artisan by night.

DAY 6:

Drive to Cacheuta and sunset horseback ride with gaucho culture in the Andes.

DAY 7:

Flight from Mendoza across the Andes to Buenos Aires.

View Journey Details